DFTX - Definium Therapeutics

Discussion in 'Stock Message Boards NYSE, NASDAQ, AMEX' started by Twiggs462, Jan 13, 2026.

  1. Twiggs462

    Twiggs462 Member

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    Rumor of 8M dark pool trade here yesterday after hours...
     
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    NJ Psilocybin Legislation Exposes Conflicts Between Advocates for Different Therapeutic Models

    https://www.lucid.news/nj-psilocybin-legislation-exposes-conflicts-between-advocates-for-different-therapeutic-models/

    There’s a lot of tension in the article around “pharma gatekeeping” vs grassroots access to natural mushrooms. But if you strip away the politics and look at what actually came out of this, it reinforces something we’ve seen over and over. When states get serious, they default to hospital-based, physician-led, FDA-aligned models.

    Bullish for the synthetic companies
     
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    Psychological Therapy Quantity and Depressive Symptom Reduction in Psychedelic-Assisted TherapyA Systematic Review and Meta-Analysis
    1. Gianluca Andri Florineth, MSc1,2; Isabell Klima, MD1; Anna Laura Boeker, MSc3

    JAMA Netw Open
    Published Online: January 21, 2026
    2026;9;(1):e2554843. doi:10.1001/jamanetworkopen.2025.54843


    Key Points
    Question Is the quantity of psychological therapy associated with symptom reduction in psychedelic-assisted therapy (PAT) for depressive symptoms?

    Findings In this systematic review and meta-analysis of 12 controlled clinical trials with 733 participants, a greater amount of preparatory psychological therapy was associated with a larger reduction of depressive symptoms following psychedelic administration. Total duration of psychological therapy as well as quantity of postpsychedelic integration sessions were not significantly associated with symptom reduction.

    Meaning These findings suggest that preparation sessions before psychedelic administration may play an important role in optimizing treatment outcomes in PAT.


    https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2844126
     
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    Freakonomics Radio (Episode 659) - Can Marty Makary Fix the F.D.A.?

    https://freakonomics.com/podcast/can-marty-makary-fix-the-f-d-a/

    At 23:59...

    "I do believe very firmly that we need to get a decision out quickly on these potentially promising treatments for P.T.S.D. We lose 8,000 veterans a year to suicide. That’s more than the entire Iraq and Afghan wars combined. The wars are over, but our men and women are still dying. We owe it to them to get a decision out quickly on some of these potentially promising treatments for P.T.S.D."

    at 30:35 they discuss autism... which means they know its an issue at large. Therefore there is some positive for DT402 in the long run.
     
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